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Russian vaccine safe, induces antibody response in small human trials: Lancet Study

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Russia Vaccine COVID-19

MOSCOW: The COVID-19 vaccine, Sputnik V, approved by Russia last month, has been shown to elicit antibody response with no serious adverse events in small human trials, according to preliminary results published in The Lancet journal on Friday.

Results from early-phase non-randomised vaccine trials in a total of 76 people show that two formulations of the vaccine have a good safety profile detected over 42 days, and induce antibody responses in all participants within 21 days.

 Secondary outcomes from the trial suggest the vaccines also produce a T cell response within 28 days, the researchers said.

The findings are based on two small phase trials lasting 42 days — one studying a frozen formulation of the vaccine, and another involving a lyophilised (freeze-dried) formulation of the vaccine, they said.

The frozen formulation is envisaged for large-scale use in existing global supply chains for vaccines, while the freeze-dried formulation was developed for hard-to-reach regions as it is more stable and can be stored at 2-8 degrees Celsius, the researchers said.

The two-part vaccine includes recombinant human adenovirus type 26 (rAd26-S) and recombinant human adenovirus type 5 (rAd5-S), which have been modified to express the SARS-CoV-2 spike protein.

The adenoviruses, which usually cause the common cold, are also weakened so that they cannot replicate in human cells and cannot cause disease, according to the researchers.

These vaccines aim to stimulate both arms of the immune system — antibody and T cell responses — so they attack the virus when it is circulating in the body, and also attack cells infected by SARS-CoV-2.

“When adenovirus vaccines enter people’s cells, they deliver the SARS-CoV-2 spike protein genetic code, which causes cells to produce the spike protein,” said study lead author Denis Logunov, from Gamaleya National Research Centre for Epidemiology and Microbiology, Russia.

“This helps teach the immune system to recognise and attack the SARS-CoV-2 virus. To form a powerful immune response against SARS-CoV-2, it is important that a booster vaccination is provided,” Logunov said.

However, Logunov said, booster vaccinations that use the same adenovirus vector might not produce an effective response.

He said this is because the immune system may recognise and attack the vector, adding this would block the vaccine from entering people’s cells and teaching the body to recognise and attack SARS-CoV-2.

“For our vaccine, we use two different adenovirus vectors in a bid to avoid the immune system becoming immune to the vector,” Logunov added.

The trials took place in two hospitals in Russia, and were open-label and non-randomised, meaning that participants knew that they were receiving the vaccine and were not assigned by chance to different treatment groups.

The trials involved healthy adults aged 18-60 years, who self-isolated as soon as they were registered, and remained in the hospital for the first 28 days of the trial from when they were first vaccinated.

In phase 1 of each trial, participants received one component of the two-part vaccine — four groups of nine participants were given the frozen or freeze-dried rAd26-S or rAd5-S component.

In phase 2, which began no earlier than five days after the phase 1 trial began, participants received the full two-part vaccine — they received a prime vaccination with the rAd26-S component on day 0, followed by a booster vaccination with the rAd5-S component on day 21.

There were 20 participants each in the frozen and freeze-dried vaccine groups, the Lancet study noted.

To compare post-vaccination immunity with natural immunity formed by infection with SARS-CoV-2, the authors obtained convalescent plasma from 4,817 people who had recovered from mild or moderate COVID-19, they said.

Both vaccine formulations were safe over the 42-day study period and well-tolerated, according to the study.

The most common adverse events were pain at the injection site, hyperthermia, headache, asthenia (weakness or lack of energy), and muscle and joint pain.

Aakash Kumar Jha is one of the youngest Digital Entrepreneur with over 06 Years of experience in Digital Sector.

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The Evolution of Digital Marketing for Luxury Brands in Dubai: A Deep Dive with IDigitalAKKI Media

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Dubai is synonymous with luxury, innovation, and extravagance. As one of the world’s most dynamic and cosmopolitan cities, it has emerged as a global hub for luxury brands that cater to a discerning clientele—ranging from local Emiratis and expatriates to high-net-worth individuals (HNWIs) and international investors. For brands operating in Dubai’s luxury market, digital marketing is not just an option; it’s a necessity.

To navigate this competitive landscape, luxury brands need to adopt cutting-edge digital strategies that cater to their audience’s refined tastes. At IDigitalAKKI Media, a leading digital marketing agency with a strong presence in both India and Dubai, we specialize in crafting bespoke strategies that help luxury brands connect with their audience, enhance brand value, and drive measurable results. In this article, we explore the evolving digital marketing landscape for luxury brands in Dubai and how IDigitalAKKI Media is leading the charge in this exciting market.


The Digital Transformation of Dubai’s Luxury Market: Insights from IDigitalAKKI Media

Dubai’s luxury market has undergone a digital revolution over the past decade, fueled by the city’s tech-savvy population and high internet penetration. However, digital marketing for luxury brands is distinct from mainstream marketing; it requires a nuanced approach that balances exclusivity, personalization, and innovation.

IDigitalAKKI Media is at the forefront of this transformation, leveraging advanced digital marketing techniques to elevate luxury brands in Dubai. Our approach is anchored in the belief that every luxury brand has a unique story that deserves to be told with finesse and creativity.

1. Personalization and Exclusivity: The Hallmarks of Luxury Digital Campaigns

IDigitalAKKI Media’s Approach:
For luxury brands, personalization is more than just a trend; it’s a cornerstone of effective digital marketing. We specialize in creating hyper-personalized campaigns that use advanced data analytics to deliver tailored content and experiences. Our focus is on making each customer feel unique and valued, which is essential in the luxury sector.

Example:
For a high-end fashion client in Dubai, IDigitalAKKI Media developed an AI-driven email marketing campaign that dynamically adjusted content based on the customer’s browsing and purchase behavior. This strategy led to a 45% increase in engagement rates and a 30% boost in sales, reinforcing the importance of personalization in luxury marketing.

2. Omnichannel Experiences: Bridging the Online and Offline Worlds

IDigitalAKKI Media’s Strategy:
Luxury shopping in Dubai is an experience that extends beyond the digital realm. To create a seamless journey for customers, we develop omnichannel strategies that integrate digital touchpoints with physical experiences. This includes personalized mobile apps, VIP customer service chatbots, and online booking systems for exclusive in-store appointments.

Example:
We implemented a digital-to-physical strategy for a luxury watch brand in Dubai that allowed VIP customers to book private in-store appointments through a mobile app. The initiative resulted in a 60% increase in foot traffic and a 25% rise in in-store sales, showcasing the power of integrated digital experiences.

3. Leveraging Augmented Reality (AR) and Virtual Reality (VR) for Immersive Experiences

IDigitalAKKI Media’s Strategy:
AR and VR have become game-changers for luxury brands looking to provide immersive experiences. IDigitalAKKI Media employs these technologies to create virtual store tours, augmented reality product try-ons, and VR-based storytelling, allowing clients to experience products uniquely and engagingly.

Example:
For a luxury real estate developer in Dubai, our team at IDigitalAKKI Media created a virtual reality experience that allowed international buyers to explore properties remotely. This led to a 40% increase in qualified leads and a faster sales cycle, demonstrating the effectiveness of immersive digital strategies.

4. High-End Content Marketing and Storytelling: Engaging Dubai’s Affluent Audience

IDigitalAKKI Media’s Edge:
Content marketing is the bedrock of luxury branding. However, to resonate with Dubai’s affluent audience, content must not only be high-quality but also culturally relevant and emotionally engaging. At IDigitalAKKI Media, we specialize in crafting compelling narratives that highlight a brand’s heritage, craftsmanship, and values.

Example:
For a luxury automotive client, we created a digital storytelling campaign that showcased the journey of their vehicles from the factory to the streets of Dubai. This campaign garnered over 2 million impressions and significantly boosted brand perception, proving the power of effective storytelling.


Challenges and Opportunities in Dubai’s Luxury Digital Marketing Landscape

The digital marketing landscape for luxury brands in Dubai presents both challenges and immense opportunities. Brands must navigate cultural sensitivities, engage high-net-worth individuals meaningfully, and maintain a consistent image across all digital platforms.

IDigitalAKKI Media excels in addressing these challenges through our localized strategies, deep market insights, and innovative digital solutions.

1. Navigating Cultural Sensitivities

IDigitalAKKI Media’s Insight:
Dubai’s luxury market is incredibly diverse, with a mix of local and international clientele. Understanding cultural nuances and creating region-specific content that respects these differences is critical for success.

Opportunity:
We have successfully partnered with local influencers and created culturally aligned campaigns that resonate with Dubai’s audience, building deeper connections and enhancing brand loyalty.

2. Reaching High-Net-Worth Individuals (HNWIs)

IDigitalAKKI Media’s Solution:
Reaching HNWIs requires a strategic approach that combines exclusivity with value. We focus on private online events, personalized communication, and luxury loyalty programs to engage this audience more effectively.

Example:
For a luxury hospitality client, we organized an exclusive online VIP event featuring a celebrity chef. The event created significant buzz and resulted in a 50% increase in bookings among high-value clients.

3. Maintaining Brand Consistency Across Digital Channels

IDigitalAKKI Media’s Strategy:
Luxury brands must maintain a consistent image across all channels. Our centralized content management system and localized content teams ensure that while brands retain their core identity, they also adapt to local tastes and preferences.

Opportunity:
This approach has enabled our clients to maintain brand consistency while reaching diverse audiences across multiple digital platforms, enhancing their brand equity in the luxury segment.


The Future of Digital Marketing for Luxury Brands in Dubai: A Look Ahead

As digital marketing continues to evolve, luxury brands in Dubai must stay ahead of the curve by embracing new trends and technologies. At IDigitalAKKI Media, we see the future of luxury digital marketing as being defined by:

1. Artificial Intelligence and Hyper-Personalization

Predictive analytics, automated content creation, and AI chatbots will redefine customer engagement. We are pioneering the use of these technologies to deliver hyper-personalized experiences that resonate with Dubai’s luxury clientele.

2. Sustainability and Digital Storytelling

Consumers are increasingly valuing sustainability and ethical practices. We are helping luxury brands in Dubai craft compelling sustainability stories that resonate with conscious consumers, driving both engagement and loyalty.

3. NFTs and Digital Ownership

Non-fungible tokens (NFTs) offer new avenues for luxury branding by creating a sense of rarity and exclusivity. We are exploring innovative ways to incorporate NFTs into our clients’ branding strategies, creating unique digital assets that appeal to Dubai’s high-net-worth individuals.


Conclusion: Elevate Your Brand with IDigitalAKKI Media

In Dubai’s rapidly evolving luxury market, staying ahead requires a strategic partner who understands both the digital landscape and the unique dynamics of the city. IDigitalAKKI Media is that partner—bringing expertise, creativity, and a results-driven approach to every campaign.

If you’re a luxury brand looking to elevate your digital presence in Dubai, connect with IDigitalAKKI Media today and let us help you craft a winning strategy that captivates, engages, and converts.

Ready to elevate your brand’s digital presence in Dubai’s luxury market? Contact IDigitalAKKI Media today to discover how our bespoke digital marketing strategies can drive exceptional growth for your business. Reach out to us at info@idigitalakki.com or visit our website at www.idigitalakki.com to schedule a consultation.

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Top 5 Reasons to Invest in Silver Coins and Bars in Australia

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Investing in silver coins and bars can be a smart financial decision for individuals looking to diversify their investment portfolio. With its stability and consistent growth, silver is an attractive investment option for both new and experienced investors. According to a survey, Australia ranks fifth globally for silver production, producing 46,782 koz in 2022. Its silver production grew at a CAGR of 4% over the past five years and is expected to grow at 3% from 2022 to 2026. So, this article will discuss the top five reasons why investing in silver coins and bars in Australia is an excellent choice for those looking to buy silver in Australia.

  1. Safe Haven Investment

Investing in silver coins and bars is a safe haven investment, which provides investors with a reliable hedge against inflation and a store of value. In times of economic uncertainty, silver has historically been a stable investment option, offering protection against the volatility of the stock market and the fluctuations of other investments. Therefore, investing in silver can help investors protect their assets during periods of economic uncertainty and maintain their purchasing power.

  1. Tangible Asset

Investing in silver coins and bars offers a tangible asset that investors can hold in their hands. This physical presence can provide a sense of security and control, as investors can see and touch their investments. Unlike stocks or other investments that are intangible and subject to market fluctuations, silver coins and bars offer a physical asset that investors can keep for the long term. Furthermore, investing in tangible assets, like silver coins and bars, can help investors diversify their portfolios and provide an additional layer of security against market volatility.

  1. Easy to Buy and Sell

Silver coins and bars are easy to buy and sell, making them a highly liquid investment option. In Australia, silver coins and bars are widely available through dealers and can be bought and sold quickly and easily. The ability to liquidate an investment quickly can be a significant advantage for investors, especially during economic uncertainty or market volatility. Therefore, investing in silver coins and bars can provide investors with a convenient and flexible investment option.

  1. Diversification

Investing in silver coins and bars provides an excellent way to diversify an investment portfolio. Diversification can help protect against risk and volatility by spreading out investments across different asset classes. Silver’s low correlation with other investments, such as stocks and bonds, makes it an ideal addition to a diversified investment portfolio. By including silver coins and bars in their investment portfolio, investors can reduce their overall risk and increase their potential for long-term returns.

  1. Potential for Growth

Investing in silver coins and bars offers the potential for growth over time, making it an attractive option for those looking to buy silver in Australia. While silver prices can be volatile in the short term, silver has historically shown consistent growth over the long term. With an increasing demand for silver in industrial and technological applications, the potential for growth in the silver market is significant. Furthermore, silver can provide investors with a steady income stream through dividends and interest payments. Therefore, investing in silver coins and bars can be a wise choice for individuals looking to build long-term wealth.

In conclusion, investing in silver coins and bars in Australia is a smart financial decision for various reasons. Silver offers a unique set of benefits that make it an attractive investment option as a safe haven investment, tangible asset, easy to buy and sell, diversification tool, and growth potential. By diversifying their investment portfolios with silver, investors can protect against risk, hedge against inflation, and potentially achieve significant long-term growth. With its stability and consistent growth, silver is an excellent investment option for individuals looking to build long-term wealth.

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The Advantages of Installing a Wall Mount Chimney in Your Kitchen

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The kitchen is the heart of the home, where families come together to share meals and create memories. However, cooking can also create unwanted smoke, steam, and odors, which can be a nuisance and a health hazard. This is where Wall Mount Range Hood comes in. These units are designed to extract smoke, steam, and odors from your cooking area, ensuring your kitchen remains clean and fresh. With various designs and features, they have become a popular choice for homeowners looking to upgrade their kitchens. This article will explore the advantages of installing a wall-mounted chimney in your kitchen.

Improved Air Quality

The advantage of installing a chimney in your kitchen is improved air quality. They are designed to extract smoke, steam, and odors from your cooking area. This feature ensures your kitchen remains clean and fresh, making it a more comfortable and pleasant cooking space. This is especially important for those with respiratory issues or allergies.

Prevent Accidents

Another significant advantage of installing a chimney is that it helps prevent accidents in the kitchen. Cooking can be dangerous, with the risk of burns and fires. The chimneys have an auto-clean function, keeping them grease and grime free. The absence of grease and grime reduces the risk of fire, making your kitchen a safer place to cook.

Aesthetically Pleasing

Wall mount chimneys come in various designs, which can add to the overall aesthetic of your kitchen. The sleek and modern design of chimneys can create a focal point in your kitchen, adding to its overall beauty. Some models also feature LED lighting that can add a stylish and contemporary touch to your kitchen.

Ease of Use

Mounted chimneys are easy to operate, making them popular among homeowners. Most of them come with a remote control, which allows you to turn the unit on and off and adjust the fan speed. This benefit makes it easier to control the extraction of smoke, steam, and odors from your cooking area.

Increased Property Value

The installation of a chimney can increase the value of your property. Potential buyers often consider a kitchen’s functionality and aesthetics when purchasing. Adding a chimney can create a modern and functional kitchen, which can be an attractive feature for potential buyers.

Energy Efficiency

They are energy-efficient, which is an essential consideration for homeowners. These units have LED lights, which are low-energy and long-lasting. They also have a low noise level, which can reduce the energy required for ventilation.

Easy Installation

Installing a chimney is relatively easy, making it a popular choice among homeowners. These units can be installed in any kitchen, regardless of the size or layout. The installation typically involves attaching the unit to the wall and connecting it to the ductwork.

Easy Maintenance

They require minimal maintenance, making them a popular choice among homeowners. These units have an auto-clean function, which keeps them free of grease and grime. The absence of grease and grime reduces the fire risk and ensures that the unit operates efficiently.

Affordable

They are an affordable option for homeowners who want to upgrade their kitchens. These units come at various prices, making them accessible to various budgets. The cost of installation is also relatively low, making it a more affordable option than other kitchen upgrades.

 In conclusion, there are many advantages to installing a Wall Mount Range Hood in your kitchen. They improve air quality, prevent accidents, are aesthetically pleasing, and are easy to use. They also higher the value of your property, are energy-efficient, easy to install and maintain, and affordable. With so many advantages, it’s no wonder that mounted chimneys are becoming a popular choice among homeowners.

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